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Type 2 Diabetes: An Overview (Beckman Conference) (Clinical Report)

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eBook details

  • Title: Type 2 Diabetes: An Overview (Beckman Conference) (Clinical Report)
  • Author : Clinical Chemistry
  • Release Date : January 01, 1999
  • Genre: Chemistry,Books,Science & Nature,
  • Pages : * pages
  • Size : 191 KB

Description

Type 2 diabetes as defined by the new classification of the American Diabetes Association (ADA) [1] is a confusing entity (1). The ADA describes it as the most common form of diabetes, occurring with increasing frequency with age, usually associated with insulin resistance and always with either relative or absolute insulin deficiency and not generally requiring insulin treatment for survival. However, this phenotypic description describes a wide variety of genotypes, which range from specific monogenic entities such as maturity-onset diabetes of youth (MODY) to polygenic metabolic disturbances (classic type 2 diabetes). In the ADA classification, when a specific etiology has been established for a phenotype, it is removed from the type 2 category and placed in the "other specific types" category (Table 1), although it may be clinically indistinguishable from type 2 diabetes. From pathophysiologic and treatment perspectives, this classification schema has limited value. Genetics and Environment


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